European explorers found sanctuary in the bountiful lands of the Southeast centuries ago. Now, these tranquil waterways allow American Cruise Lines to provide guests with an exploration of history and natural beauty. Discover Southern charm as we cruise the Intracoastal Waterway or the early American ideal on our Chesapeake Bay Cruise. Our southern U.S. river cruises bring guests to unique, historic, and bucket-list destinations such as Tangier Island, Charleston, SC, Cambridge, MD, Washington D.C., Baltimore, and St. Augustine, FL.
Charleston, SC to Amelia Island, FL
Washington, DC to Washington, DC
Baltimore, MD to Jacksonville, FL
St Petersburg, FL to St Petersburg, FL
Jacksonville, FL to Jacksonville, FL
St Petersburg, FL to Jacksonville/Amelia Island, FL
Baltimore, MD to Washington, DC
*Offer Valid Only on New Bookings on Select Dates
As the southernmost point in the continental U.S., it’s no wonder Key West is an absolute paradise. Once a haven for pirates in the 1800s, it quickly became one of the wealthiest cities per capita in America due to its lucrative salvage industry. Today, its colorful streets, Hemingway’s former home, and century-old bars capture the rebellious, free-spirited charm that has attracted artists, writers, and everyone in between for generations.
The nation’s capital is a city where history is etched into every corner. Monuments and museums fill the National Mall, while cobblestone streets in Georgetown recall its colonial roots. Home to the White House and Supreme Court, Washington, D.C. is a place where American ideals and stories of progress come alive.
Charleston’s cobblestone streets and colorful homes transport you back to the past. As one of America’s oldest cities, its history is filled with tales of colonial grandeur, Revolutionary battles, and Civil War turmoil. The scent of jasmine floats through the historic districts, as it decorates centuries-old churches and preserved mansions standing as timeless reminders of its historical impact.
Known as the birthplace of the national anthem, the city’s history is tightly woven with American identity. Its Inner Harbor is surrounded by historic sites like Fort McHenry, where “The Star-Spangled Banner” was penned, and neighborhoods like Fell’s Point, filled with 18th-century rowhouses that echo the city’s seafaring roots.
Packing for a Southeast cruise will be dependent on the season. If cruising the southern USA during warmer months, it's important to bring lightweight clothing, sun protection, and light layers. If you're cruising during the colder months, make sure to pack layers to adjust to the changing temperature. No matter when you cruise, it's important to pack comfortable shoes and items like a rain jacket and umbrella to ensure you're ready for all weather.
There are three key seasons to cruise the Southeast: spring, fall, and winter. Springtime is great for mild weather, blooming flowers, and lighter crowds. Fall is the perfect time to see the magnificent leaves turn without the cold. Winter cruises offer a warm escape, festive holiday cheer, and serene coastal landscapes.
Our Southeast itineraries leave from Charleston, SC; Washington, D.C.; Baltimore, MD; Amelia Island, FL; St. Petersburg, FL; and Jacksonville, FL.
American Cruise Lines' modern ships are a testament to premier nautical engineering, luxurious comfort, and the river cruising convenience. Our fleet of American riverboats, paddlewheelers, and small cruise ships offer the latest amenities, state-of-the-art navigation, and safety equipment.
We emulate the southern charm of this region on all of our cruises with our exceptional personalized service and hospitality. As you cruise in perfect comfort to ports like Charleston, SC, and Savannah, GA, enjoy spacious amenities, a private balcony, and an intimate oasis aboard our fleet of award-winning small ships.
You will experience an authentic crab fest in Baltimore and delicious oysters in Charleston, but you will also taste exquisite cuisine onboard our ships. Our team of award-winning chefs locally sources ingredients with food that brings every region to life.
Musicians, historians, and naturalists join every cruise, creating an entertaining onboard experience. Our cruises in this region focus heavily on southern history and culture, where even the most self-proclaimed history buffs will learn something new.
