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US River Cruises

American Cruise Lines provides guests an extraordinary river cruising experience while exploring the historic waterways of the United States. Cruise in comfort aboard our modern fleet of river boats and paddlewheelers. Enjoy luxurious accommodations, exceptional cuisine, and personalized service on every cruise. View All Cruises

Featured Cruises

Mississippi River Cruises

Cruise the Mississippi River in grand style aboard a modern paddlewheeler filled with historic grandeur. Explore the vibrant culture and incredible history of the Mississippi River with a cruise from New OrleansMemphisNashvilleSt PaulSt Louis, or Cincinnati. Gaze upon the riverbanks from your private balcony, the paddlewheel lounge, or up on the upper deck with friends. View all Mississippi River Cruises

Lewis and Clark Cruises

Navigate the legendary route pioneered by Lewis and Clark as we cruise the Columbia and Snake Rivers. Discover the majestic Columbia River Gorge, Multnomah Falls, Mount St. Helens, plus guided tours of historic Fort Clatsop, and the iconic frontier town of Pendleton, OR. 2016 Cruise Schedules

Puget Sound and San Juan Islands Cruise

Cruising Puget Sound is an unforgettable adventure filled with natural beauty and wildlife. Join us aboard American Spirit as we explore everything the region has to offer from the gardens of Victoria to whale watching on the sundeck. Join us for our Spring Food and Wine, or Tulip Festival cruises beginning April 2016. See Cruise Schedules

Explore the protected waterways of the Southeast United States with a memorable cruise along the East Coast Intracoastal Waterway, Chesapeake Bay or the Great Rivers of Florida. Captivating experts and guided shore excursions illuminate local history and culture as we explore these iconic waterways. Learn more

Conde Nast Readers Choice awards finalist 2014 Travel Weekly Magellan Gold Award 2014
Porthole Readers Choice Award Winner 2014